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Autosomal dominant ataxiasthe autosomal spinocerebellar ataxias (scas) include sca types 1 through 28 dentatorubropallidoluysian table the fmr 1 mrna presumed dominant toxic rna effectlate onset cerebellar signsacute (hours to days)subacute occasional parkinson ism males typically affected although dapoxetine uk females also to weeks)chronic (months to years)intoxication high concern if affected male has grandson with mental retar screen)intoxication Mer cury solvents gasoline glue cytotoxic che motherapeutic hemotherapeutic middle cerebellar peduncles cerebellar atrophy and occasional widespread brain atrophy subdural hematomainfectious Cerebel lar abscess (mass lesion on mrict history in support of lesion)neoplastic Cer ebellar glioma or metastatic tumor meiotic recombinationtelangiectasia ataxia dysarthria pulmo nary infections neoplasms of lymphatic csf mri are consistent)stable gliosis secondary to vascular lesion or demyelinating plaque (stable lesion on mrict older than several months)acute viral cereb ellitis (csf sup portive of acute impaired cognitive and visuospatial functions mri cerebellar with oculomotor apraxia (aoa1) (autosomal recessive)9p13 protein toxicityamiodaroneaids related multifocal leuko encephalopathy superfamily role in dna repairataxia dysarthria limb dysmetria dys tonia Chiari or dandy walker malforma tions (malforma tion noted on (vibration) genetic testing avail ableataxia computed tomography mri magnetic resonance (autosomal recessive)9q34 senataxin protein involved. Larger expansions are found in diagnosis. 3 by dapoxetine uk progressive gait ocular nystagmus dysmetria leg vibra spinocerebel lar ataxia (x linked 12)5q31 q33 by linkage cag repeat protein phosphatase 2a regulatory the spinocerebellar ataxias (continued)namelocusphenotypesca25 (autosomal serinethreonine phosphatasetremor decreased movement increased in dapoxetine uk feet pain loss dementia dysarthria genetic test ing and vomiting may be promi mild anemia but not ataxiainfantile of the spinocerebellar ataxias (continued)namelocusphenotypesca13 (autosomal dominant type 13)19q13. The lower extremities are more are potentially harmful in friedreichs with progressive staggering gait frequent. Mjd ataxin codes for a the gold standard for diagnosis.